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Merck KGaA
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Becton Dickinson
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rPeptide
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Biomeda corporation
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AXON Neuroscience
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FUJIFILM
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Merck KGaA
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Meso Scale Diagnostics LLC
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Synaptic Systems
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MediMabs Inc
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Image Search Results
Journal: Molecular Pharmacology
Article Title: Reduced Myelination and Increased Glia Reactivity Resulting from Severe Neonatal Hyperbilirubinemia
doi: 10.1124/mol.115.098228
Figure Lengend Snippet: Kernicterus mice present axonal loss and decreased myelination. (A) Serial sagittal images of control and kernicterus mice. Each image represents a montage of 100–150 images at 10× magnification. Brain sections (3 μm) of each animal were immunolabeled to identify neuronal axons (neurofilaments, green, middle panel) and myelin basic protein (MBP, red, bottom panel). Top panel represents the superposition of neurofilaments, MBP and DAPI staining, the last used for nuclei counterstain (blue). Scale bar, 700 μm. (B) Expression of MBP in cerebellum. RNA was used for real-time PCR analysis and total cellular protein was used for Western blot analysis.
Article Snippet: Antibodies used were a rabbit anti-human UGT1A1 ( Chen et al., 2013 ) and a
Techniques: Immunolabeling, Staining, Expressing, Real-time Polymerase Chain Reaction, Western Blot
Journal: Molecular Pharmacology
Article Title: Reduced Myelination and Increased Glia Reactivity Resulting from Severe Neonatal Hyperbilirubinemia
doi: 10.1124/mol.115.098228
Figure Lengend Snippet: Reduced myelination and increased glial reactivity. Representative images from cerebellum, medulla and corpus callosum from control and kernicterus mice immunolabeled to identify (A) neurons (neurofilament, red) and myelin basic protein (MBP, green), (B) microglia (Iba-1+ staining, red) and MBP (green), and (C) astrocytes (GFAP+ staining, red) and MBP (green). Nuclei were counterstained with DAPI dye (blue).
Article Snippet: Antibodies used were a rabbit anti-human UGT1A1 ( Chen et al., 2013 ) and a
Techniques: Immunolabeling, Staining
Journal: Molecular Pharmacology
Article Title: Reduced Myelination and Increased Glia Reactivity Resulting from Severe Neonatal Hyperbilirubinemia
doi: 10.1124/mol.115.098228
Figure Lengend Snippet: Myelination and glial reactivity changes in kernicterus mice. (A) Three different regions were specified, Region 1 (white matter nodes), region 2 (middle of white matter tracts), and region 3 (white matter terminals). Sections from control and kernicterus mice were immunolabeled to identify (B) neurons (neurofilament, red) and myelin basic protein (MBP, green), (C) microglia (Iba-1+ staining, red) and MBP (green), and (D) astrocytes (GFAP+ staining, red) and MBP (green). Nuclei were counterstained with DAPI dye (blue). Representative images from the three white mater regions are shown. Scale bar represents 25 µm.
Article Snippet: Antibodies used were a rabbit anti-human UGT1A1 ( Chen et al., 2013 ) and a
Techniques: Immunolabeling, Staining